产品货号：
Z22108
中文名称：
ODF2抗体
英文名称：
Anti-ODF2 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ODF2 Antibody |
| 指标别名 | Cenexin;ODF2;ODF2/1;ODF2/2;ODF84;Outer dense fiber protein 2 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | ODF2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a truncated recombinant protein hCenexin1. |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This antibody was purified from monospecific antiserum by protein-A purified immunoaffinity chromatography.It is directed against,and shows specific reactivity for,human Cenexin-1 protein.A BLAST analysis was used to suggest cross-reactivity with Cenexin-1 from human,chimpanzee,mouse,rat,bovine sources based on 100% homology with the immunizing sequence.Reactivity with Cenexin-1 protein from other sources has not been determined. |
| 浓度 | 1.53mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | This antibody is suitable for Cancer,Immunology and Nuclear Signaling research.Cenexin-1 (ODF84) and cenexin-2 are splicing variants that are expressed from the same genetic locus Outer Dense Fiber protein 2 (ODF2).Cenexin-1 and cenexin-2,regarded as centriolar proteins.Cenexin-1,a 93-kD variant of ODF2,is the major form of cennexin expressed in various somatic cells and tissues and associates with centrosomes.Cenexin-1 contains a unique C-terminal extension that appears to play a critical role in recruiting mitotic regulators such as polo-like kinase 1.In contrast,ODF2,a 70-kDa protein,is a major component of sperm tail cytoskeleton and abundantly expressed in testis.Additional evidence suggests that both of these proteins play important role in primary cilia formation.The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation.Defects in the outer dense fibers lead to abnormal sperm morphology and infertility.Cenexin-1 is one of the major outer dense fiber proteins.Multiple protein isoforms are encoded by transcript variants of the cenexin gene;however,not all isoforms and variants have been fully described. |
| Uniprot ID | Q5BJF6 |
| 推荐稀释比 | ELISA:1:500 - 1:10,000 WB:1:500～1:2000 |
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